InVivoMAb anti-Human CA125/MUC16 Antibody
- Cat. No.:RB9THV601010
- Price:Negotiable
- Clicks:380
Product Detail
Product Parameters
| Product Description | AR9.6 is a humanized monoclonal antibody targeting MUC16, with preclinical efficacy against MUC16-associated cancers. It binds strongly to the SEA domain 5 tandem repeat region of MUC16, reduces pancreatic cancer (PDAC) cell migration, and mediates tumor cell killing via ADCC and CDC. In orthotopic PDAC mouse models, AR9.6 significantly decreases tumor growth and proliferation. |
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| Form | Liquid |
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| Host Species | Human |
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| Clonality | Monoclonal |
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| Isotype | IgG1 |
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| Purity | >95% as determined by SDS-PAGE. |
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| Purification | Protein A/G purified from cell culture supernatant. |
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| Concentration | 1 mg/ml |
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| Endotoxin Level | Please contact with the lab for this information. |
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| Applications | ELISA, FCM, Neutralization |
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| Species Reactivity | Human |
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| Target | Mucin-16, CA-125, Ovarian carcinoma antigen CA125, CA125, MUC-16, Ovarian cancer-related tumor marker CA125, MUC16 |
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| Storage Buffer | 0.01M PBS, pH 7.4. |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
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| Accession Number | Q8WXI7 |
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| Note | For research use only. Not suitable for clinical or therapeutic use. |
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For Research Use Only. Not for Diagnostic Procedures.
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