InVivoMAb anti-Human CD40/TNFRSF5 Antibody
- Cat. No.：RB9THB782010
- Price：Negotiable
- Clicks：305
Product Detail
Product Parameters
| Product Description | Iv0136 is a bispecific, humanized monoclonal antibody engineered for cancer immunotherapy. It simultaneously targets CD40 and 4-1BB (CD137), enabling coordinated activation of antigen-presenting cells and T cells to enhance anti-tumor immune responses. By engaging these two pathways, Iv0136 is being investigated for its potential to modulate immune activity in both oncology and autoimmune research settings. Preclinical studies indicate that dual CD40/4-1BB targeting may promote tumor control and influence immune regulation in models of diseases such as rheumatoid arthritis and multiple sclerosis. |
|---|---|
| Form | Liquid |
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Human |
| Target | Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40 |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | P25942 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
Related Products: