InVivoMAb anti-Human CXCL12/SDF-1 beta Antibody
- Cat. No.：RB9THW376010
- Price：Negotiable
- Clicks：488
Product Detail
Product Parameters
| Product Description | Iv0090 is a human IgG monoclonal antibody targeting CXCL12α, β, and γ. It blocks CXCL12 binding to CXCR4 and CXCR7 and inhibits CXCL12-driven cell migration in vitro. In vivo, Iv0090 significantly inhibits tumor growth and metastasis, reduces arthritis severity in mouse CIA models, and decreases laser-induced choroidal neovascularization by 50%. |
|---|---|
| Form | Liquid |
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 2.07 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Human |
| Target | Intercrine reduced in hepatomas, hSDF-1, Stromal cell-derived factor 1, SDF-1, Pre-B cell growth-stimulating factor, SDF1, SDF1A, C-X-C motif chemokine 12, SDF1B, CXCL12, IRH, PBSF, hIRH |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | P48061 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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