InVivoMAb anti-Human IFN-gamma Antibody
- Cat. No.：RB9THF813010
- Price：Negotiable
- Clicks：330
Product Detail
Product Parameters
| Product Description | Iv0049 is a humanized monoclonal antibody that targets and neutralizes interferon-gamma (IFN-γ), a cytokine associated with inflammatory pathways. It has been investigated for potential use in autoimmune diseases such as Crohn’s disease. By binding IFN-γ, Iv0049 reduces downstream inflammatory signaling and its detrimental effects on intestinal barrier integrity. Early clinical studies have reported signs of therapeutic activity and generally manageable tolerability, although some serious adverse events, including disease exacerbation, were observed. Iv0049 has not been described as a currently marketed therapy, and its broader clinical development status remains unclear. |
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| Form | Liquid |
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization, FCM |
| Species Reactivity | Human |
| Target | Interferon gamma, IFN-gamma, Immune interferon, IFNG, IFN-γ |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | P01579 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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