InVivoMAb anti-Mouse GIPR Antibody
- Cat. No.：RB9TMW595010
- Price：Negotiable
- Clicks：270
Product Detail
Product Parameters
| Product Description | GIPR is a key metabolic regulator involved in nutrient sensing and energy balance. Iv0037 is a potent, fully antagonistic anti-mouse GIPR monoclonal antibody that locks the receptor’s extracellular domain in a unique auto-inhibitory conformation. By partially blocking ligand binding and mimicking the receptor’s C-terminal stalk, Iv0037 stabilizes GIPR in a novel inhibited state. In diet-induced obese mice, Iv0037 treatment reduces body-weight gain and improves metabolic profiles. |
|---|---|
| Form | Liquid |
| Host Species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 1 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Mouse |
| Target | Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, Gipr |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | Q0P543 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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