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InVivoMAb Anti-HIV1 gp120/Glycoprotein 120 (Iv0038)
- Cat. No.：RB9TVK617020
- Price：Negotiable
- Clicks：185
Product Detail
Product Parameters
| Product Description | The Iv0038 monoclonal antibody recognizes HIV-1 gp120, a heavily glycosylated ~120 kDa envelope glycoprotein that forms the outer subunit of the viral Env complex. gp120 mediates viral attachment by binding to the CD4 receptor and coreceptors such as CCR5 or CXCR4 on target cells, making it a key determinant of viral entry and tropism. By targeting conformational epitopes on gp120, Iv0038 can neutralize HIV-1, blocking the interaction between gp120 and host receptors and thereby preventing fusion and subsequent infection. Because gp120 is exposed on the virion surface and undergoes conformational changes during receptor engagement, antibodies like Iv0038 are valuable tools for studying viral entry mechanisms, Env antigenicity, and immune responses to HIV-1. |
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| Form | Liquid |
| Host Species | Human |
| Clonality | Monoclonal |
| Isotype | IgG1, lambda2 |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Concentration | 2.2 mg/ml |
| Endotoxin Level | Please contact with the lab for this information. |
| Applications | ELISA, Neutralization |
| Species Reactivity | Human immunodeficiency virus 1 (HIV-1) |
| Target | Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, SU, Glycoprotein 120, gp120, Transmembrane protein gp41, TM, Glycoprotein 41, gp41, env |
| Storage Buffer | 0.01M PBS, pH 7.4. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Accession Number | Q03805 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
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