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Anti-Ramucirumab Polyclonal Antibody

  • Cat. No.:RB9TAW338014
  • Price:Negotiable
  • Clicks:456

Product Detail

Product Parameters

FormLiquid
Host SpeciesRabbit
ClonalityPolyclonal
IsotypeIgG
PurificationPurified by antigen affinity column.
Endotoxin LevelPlease contact with the lab for this information.
ApplicationsELISA
SpecificityThe product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
ImmunogenRamucirumab
Storage Buffer0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and StorageThe product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Product Usage InformationELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
Accession NumberCAS: 947687-13-0
BackgroundRamucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
Alternative NamesRabbit polyclonal to REGN-10987.
NoteFor research use only.
For Research Use Only. Not for Diagnostic Procedures.

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