Recombinant Mouse SAP (C-6His)
- Cat. No.：EPT196
- Price：Negotiable
- Clicks：787
Product Detail
Basic Information
| Size | 50ug |
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| Expression Host | Human Cells |
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| Tag | C-6His |
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Physical Properties
| Molecular Weight | 24.9 KDa |
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| Apparent Molecular Weight | 28-32 KDa, reducing conditions |
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| Form | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 50mM Imidazole, 5% Trehalose, 20% Glycerol, pH8.0. |
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| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
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Activity & Endotoxin
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
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Storage & Shipping
| Storage | Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles. |
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| Shipping Condition | The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below. |
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Detailed Description
| Background | Pentraxin 2 (PTX2), also known as Serum amyloid P (SAP), is a highly conserved, naturally circulating plasma protein and a soluble pattern recognition receptor of the innate immune system. The unique binding activities indicated that it may play an important role in the removal of damaged tissue. PTX2 belongs to the pentraxin family, is universally present in amyloid deposits. Mouse with targeted deletion of the PTX2 gene shows retarded and reduced induction of experimental reactive systemic (AA type) amyloidosis confirmed that it does indeed contribute to pathogenesis of amyloidosis and is a valid therapeutic target. In recent discovery, PTX2 can be used as a powerful antifibrotic agent to regulate certain monocyte differentiation states. |
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