Recombinant Mouse IL-23
- Cat. No.：EPT183
- Price：Negotiable
- Clicks：1341
Product Detail
Basic Information
| Size | 10ug |
|---|---|
| Expression Host | Human Cells |
| Tag | NA |
Physical Properties
| Molecular Weight | 19.7&35.8 KDa |
|---|---|
| Apparent Molecular Weight | 18&40-55 KDa, reducing conditions |
| Form | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
Activity & Endotoxin
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
|---|---|
| Activity | Measured by its ability to induce STAT reporter activity in 293F human embryonic kidney cells.The ED50 for this effect is 501.08 ng/ml. |
Storage & Shipping
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| Shipping Condition | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Detailed Description
| Background | Interleukin 23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12. The p19 subunit has homology to the p35 subunit of IL-12, as well as to other single chain cytokines such as IL-6 and IL-11. The p40 subunit is homologous to the extracellular domains of the hematopoietic cytokine receptors. Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naive and memory human T cells, the effects of IL-23 is restricted to memory T cells. |
|---|
Related Products:
| Product Name | Clicks |
|---|---|
| 氨苄青霉素-BSA抗原 | 5368 |
| 四环素-BSA抗原 | 5445 |
| 金霉素-BSA抗原 | 5631 |
| 土霉素-BSA抗原 | 5298 |
| 强力霉素-BSA抗原 | 5414 |
| 可替宁-BSA（或OVA）抗原 | 5393 |
| 己烯雌酚-BSA（或OVA）抗原 | 5203 |
| 睾酮-BSA（或OVA）抗原 | 5246 |
| 胆固醇-BSA（或OVA）抗原 | 5405 |
| 孕酮（PROG）（黄体酮）-BSA（或OVA）抗原 | 5372 |
| 雌二醇（E2）-BSA（或OVA）抗原 | 5011 |
| 雌三醇（E3）-BSA（或OVA）抗原 | 5486 |
| L-甲状腺素（T4）-BSA（或OVA）抗原 | 5675 |
| 三碘甲状腺素T3-BSA（或OVA）抗原 | 5284 |
| 地塞米松-BSA（或OVA）抗原 | 5588 |
| 孔雀石绿-BSA（或OVA）抗原 | 5409 |
| 无色孔雀石绿-BSA（或OVA）抗原 | 5501 |
| 链霉素-BSA（或OVA）抗原 | 5202 |
| 喹乙醇-BSA（或OVA）抗原 | 5422 |
| 苏丹红1-BSA（或OVA）抗原 | 5310 |