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Recombinant Mouse Asprosin (N-8His)

  • Cat. No.:EPT137
  • Price:USD $ 5,280.00
  • Clicks:1120

Product Detail

Basic Information

Size50ug
Expression HostHuman cells
TagN-8His

Physical Properties

Molecular Weight16.9 KDa
Apparent Molecular Weight30 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
PurityGreater than 85% as determined by reducing SDS-PAGE.

Activity & Endotoxin

Endotoxin LevelLess than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Storage & Shipping

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Detailed Description

BackgroundAsprosin is a protein hormone that is produced by white adipose tissue in mammals (and potentially by other tissues), which is then transported to the liver and stimulates it to release glucose into the blood stream. In the liver asprosin activates rapid glucose release by a cAMP-dependent pathway. The glucose release by the liver into the blood stream is vital for brain function and survival during fasting. People with neonatal progeroid syndrome lack asprosin, while people with insulin resistance have it in abundance. In animal tests asprosin showed potential for treating type 2 diabetes. When antibodies targeting asprosin were injected into diabetic mice, blood glucose and insulin levels improved.
For Research Use Only. Not for Diagnostic Procedures.

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