Recombinant Cynomolgus TSLP (C-6His)
- Cat. No.：EPT093
- Price：USD $ 840.00
- Clicks：1062
Product Detail
Basic Information
| Size | 10ug |
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| Expression Host | E.coli |
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| Tag | C-6His |
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Physical Properties
| Molecular Weight | 16.2 KDa |
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| Apparent Molecular Weight | 16 KDa, reducing conditions |
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| Form | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4. |
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| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
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Activity & Endotoxin
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
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| Activity | Immobilized Anti-Human TSLP mAb (Cat#NC066) at 2μg/ml (100 μl/well) can bind Cynomolgus TSLP-His (Cat#CR62). The ED50 of Cynomolgus TSLP-His (Cat#CR62) is 4.48 ng/ml. |
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Storage & Shipping
| Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
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| Storage | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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| Shipping Condition | The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below. |
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Detailed Description
| Background | Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required. |
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