Recombinant Rat IL-2 (C-6His)
- Cat. No.：EPT090
- Price：USD $ 2,700.00
- Clicks：1128
Product Detail
Basic Information
| Size | 50ug |
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| Expression Host | Human Cells |
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| Tag | C-6His |
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Physical Properties
| Molecular Weight | 16.3 KDa |
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| Apparent Molecular Weight | 14-16 KDa, reducing conditions |
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| Form | Supplied as a 0.2 μm filtered solution of 5mM NaH<sub>2</sub>PO<sub>4</sub>, 5mM Citric acid, 150mM NaCl, pH 4.0. |
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| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
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Activity & Endotoxin
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
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Storage & Shipping
| Storage | Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles. |
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| Shipping Condition | The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below. |
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Detailed Description
| Background | Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. |
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