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Recombinant HIV gp120 (C-8His)

  • Cat. No.:EPT033
  • Price:USD $ 480.00
  • Clicks:677

Product Detail

Basic Information

Size10ug
Expression HostHuman Cells
TagC-8His

Physical Properties

Molecular Weight57 KDa
Apparent Molecular Weight90-140 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
PurityGreater than 95% as determined by reducing SDS-PAGE.

Activity & Endotoxin

Endotoxin LevelLess than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Storage & Shipping

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Detailed Description

BackgroundEnvelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequence inhibit immune function in vitro and in vivo.
For Research Use Only. Not for Diagnostic Procedures.

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