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Recombinant Mouse EpCAM (C-Fc)

  • Cat. No.:EPT017
  • Price:USD $ 1,800.00
  • Clicks:796

Product Detail

Basic Information

Size50ug
Expression HostHuman Cells
TagC-Fc

Physical Properties

Molecular Weight54.8 KDa
Apparent Molecular Weight60-80 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
PurityGreater than 95% as determined by reducing SDS-PAGE.

Activity & Endotoxin

Endotoxin LevelLess than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

Storage & Shipping

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

Detailed Description

BackgroundEpithelial Cellular Adhesion Molecule (Ep-CAM), also known as EGP314, mEGP314, Protein 289A, Tumor-associated calcium signal transducer 1, CD326, belongs to the EPCAM family. Its’ monomer subunit structure interacts with phosphorylated CLDN7. Ep-CAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. It also up-regulates the expression of FABP5, MYC and cyclins A and E. The post-translational modification glycosylation at Asn-198 is crucial for protein stability.
For Research Use Only. Not for Diagnostic Procedures.

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