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Recombinant Human LAIR2 (C-Fc)

货号:EPT260
  • Price:Negotiable
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Product Detail

基本信息

Size50ug
Expression HostHuman Cells
TagC-Fc

物理性质

Molecular Weight41 KDa
Apparent Molecular Weight45-55 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
PurityGreater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

Endotoxin LevelLess than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

BackgroundLeukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2) is a secreted, 131 amino acid protein that contains one Ig-like C2 type domain, making it a member of the Ig superfamily. When compared to LAIR-1, its transmembrane counterpart, it shares 83% amino acid identity across the signal sequence and extracellular domains; although one is secreted and one is membrane-bound, the two LAIR proteins are thought to have arisen from a common gene ancestor and appear to share similar adhesion profiles. This suggests that LAIR-2 may compete with LAIR-1 for ligand binding. A 114 amino acid alternate splice form of LAIR-2 is truncated at the C terminus, but retains the entire Ig domain. The expression profile of these splice forms, and the presence of orthologs in other species, have not been reported.