Product Detail

基本信息

Size	10ug
Expression Host	E.coli
Tag	NA

物理性质

Molecular Weight	12.9 KDa
Apparent Molecular Weight	12 KDa, reducing conditions
Form	Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 30% Glycerol, 1mM DTT, pH 8.0.
Purity	Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

Endotoxin Level	Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.

储存与运输

Storage	Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
Shipping Condition	The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

详细说明

Background

Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies showed that the coexpression of the hS100A7 and hS100A15 in psoriasis suggests that both proteins participate in keratinocyte maturation, proliferation and/or skin inflammation.