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Recombinant Human IGF-I (67AA)

货号:EPT091
  • Price:Negotiable
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Product Detail

基本信息

Size50ug
Expression HostE.coli
Tag67AA

物理性质

Molecular Weight7.3 KDa
Apparent Molecular Weight9 KDa, reducing conditions
FormLyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc, pH 4.5
PurityGreater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

Endotoxin LevelLess than 0.05 ng/µg (0.5 EU/µg) as determined by LAL test.

储存与运输

ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
StorageLyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping ConditionThe product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below.

详细说明

BackgroundInsulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor protein containing N-terminal and C-terminal propeptide regions. Mature human IGF-I consisting of 70 amino acids with 94% identity with mouse IGF1 and exhibits cross-species activity. IGF1 binds IGF-1R, IGF-2R, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF1 expression is regulated by growth hormone.