Product Detail
基本信息
| Size | 10ug |
|---|---|
| Expression Host | Human Cells |
| Tag | C-6His |
物理性质
| Molecular Weight | 77.4 KDa |
|---|---|
| Apparent Molecular Weight | 90 KDa, reducing conditions |
| Form | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 2mM CaCl<sub>2</sub>, 150mM NaCl, 0.05% Brij35(w/v), pH 7.5. |
| Purity | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| Endotoxin Level | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
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储存与运输
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
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| Shipping Condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| Background | Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis. |
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