Product Detail

基本信息

Size	10ug
Expression Host	E.coli
Tag	NA

物理性质

Molecular Weight	15.5 KDa
Apparent Molecular Weight	14 KDa, reducing conditions
Form	Lyophilized from a 0.2 μm filtered solution of 10mM sodium citrate, pH 4.0.
Purity	Greater than 95% as determined by reducing SDS-PAGE.

活性与内毒素

Endotoxin Level	Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Activity	Loaded Human IL-2RA-Fc(Cat#CJ78) on Protein A Biosensor, can bind Human IL-2(Cat#C013) with an affinity constant of 17.0 nM as determined in BLI assay.

储存与运输

Reconstitution	Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping Condition	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

详细说明

Background

Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.