Product Detail
基本信息
| Size | 50ug |
|---|---|
| Expression Host | E.coli |
| Tag | N-6His |
物理性质
| Molecular Weight | 17.9 KDa |
|---|---|
| Apparent Molecular Weight | 18 KDa, reducing conditions |
| Form | Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4. |
| Purity | Greater than 80% as determined by reducing SDS-PAGE. |
储存与运输
| Storage | Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
|---|---|
| Shipping Condition | The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| Background | Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing. |
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